Endocrine Abstracts

Introduction: Some studies suggest a possible link between autoimmune thyroid disease (AITD) and thyroid cancer (TC). However, existing data is inconsistent, and no consensus exists regarding this question.Objective: The aim of this study was to analyze the association between TC and AITD, namely Hashimoto’s thyroiditis (HT) and Graves’ disease (GD).Methods: We conducted a retrospective and observational study of all pati...

Introduction: Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare entity. Up to 1/3 of patients with incidental bilateral adrenal nodules presents biochemical evidence of hypercortisolism responsible for obesity, diabetes mellitus (DM), arterial hypertension or dyslipidemia. Its insidious course and nonspecific signs explain the underdiagnosis of this entity.Objective: To describe the case of a patient with metabolic syndrome (MS) with h...

Introduction: Malnutrition and sarcopenia are interrelated and frequent in hospital settings, being related to a higher morbimortality. CIPA nutritional screening (performed at the Hospital Universitario Nuestra Señora de Candelaria) is positive when one or more of the following criteria is met: a) decreased oral intake in 72 h (<50%), b) albumin <3 g/dl, and c) BMI <18.5 g/m2 or mid-upper arm circumference (MUAC) ≤ 22.5 cm.<p class="abste...

Introduction: Morbid obesity is a highly prevalent disease, with bariatric surgery being a fundamental pillar in its treatment.Objectives: To analyze the results of weight loss at 5 years in patients operated by gastric bypass and sleeve at the Regional University Hospital of Malaga.Methods: This is a retrospective observational study, where 104 patients with morbid obesity who underwent bariatric surgery at the Regional University...

Introduction: Obstructive sleep apnea-hypopnea syndrome (OSAHS) and obesity are two pathologies increasingly prevalent in population related to each other. Obesity is present in between 60-90% of patients diagnosed with OSAHS being the most important modifiable risk factor. Obesity influences the risk factor for OSAHS degree of severity, increasing its severity by up to 30%. The degree of relation between both pathologies, we created a protocol Endocrinology and Pneumology ser...

Introduction: Paragangliomas are rare tumors originated from extraadrenals chromaffin cells. Most are sporadic, but between 30% and 50% are associated with hereditary syndromes. Mutations in the succinate gene dehydrogenase (SDH) have been identified as a cause of the hereditary paraganglioma-pheochromocytoma syndrome.Material and methods: Descriptive study of case series of patients belonging to the Southern Health Area of Seville with mutations in the ...

IntroductionMixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) of the pancreas are composed of two morphologically different components, each representing at least 30% of the tumor: ductal or acinar adenocarcinoma and neuroendocrine neoplasm (NEN). They are extremely rare tumors whose etiopathogenesis and biological behavior are not fully understood. Given its rarity, we describe a case of insulinoma in the context of MiNEN....

Multiple endocrine neoplasia type 1 (MEN-1) is characterized by an increased predisposition to the development of tumors of the endocrine tissues, such as parathyroid glands, anterior pituitary, and duodenopancreatic neuroendocrine tumors. It is an autosomal dominant disorder due to germline mutations in the MEN-1 tumor suppressor gene. This gene encodes the menin protein, which is involved in cell growth and differentiation, and in sensing or repairing DNA damage. We present ...

Introduction: A third of pituitary adenomas are non-functioning. Classification depends on adenohypophyseal hormones expression and transcription factors.Aim: Characterize silent pituitary macroadenomas cases regarding their clinical data, treatment, histopathology and prognosis.Methods: We revised clinical process of patients followed in CHULC. Cases with non-access to clinical follow-up registries or exams were excluded.<p cl...

Primary amenorrhea is characterized by the absence of menstruation after the age of 14 without the development of secondary sexual characteristics or after the age of 16 with the development of these. Hypogonadotropic hypogonadism (HH) corresponds to an uncommon etiology of primary amenorrhea. In HH, the differential diagnosis includes Kallmann Syndrome, isolated hypogonadotropic hypogonadism and CHARGE Syndrome. The CHARGE syndrome corresponds to an extremely rare syndrome, w...